Donna M. Dambach: search on Z-Library

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1

Ascites, premature emergence, increased gonadal cell apoptosis, and cytochrome P4501A induction in pink salmon larvae continuously exposed to oil-contaminated gravel during development

Marty, Gary D., Hinton, David E., Short, Jeffrey W., Heintz, Ronald A., Rice, Stanley D., Dambach, Donna M., Willits, Neil H., Stegeman, John J.

Journal:

Canadian Journal of Zoology

Year:

1997

Language:

english

File:

PDF, 757 KB

english, 1997

2

Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications

Ford, Kevin A., Ryslik, Gregory, Sodhi, Jasleen, Halladay, Jason, Diaz, Dolo, Dambach, Donna, Masuda, Melisa

Journal:

Drug Metabolism Reviews

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

3

Carcinogenicity assessment of the Hedgehog pathway inhibitor, vismodegib in Tg.rasH2 mice and Sprague-Dawley rats

Li, Jinze, Morinello, Eric, Larsen, Thomas, Frost, Denzil, Caro, Ivor, Gould, Stephen, Wong, Lisa, Hendricks, Angela, Dybdal, Noel, Dambach, Donna, Schutten, Melissa

Journal:

Regulatory Toxicology and Pharmacology

Year:

2017

Language:

english

File:

PDF, 891 KB

english, 2017

4

Using Genetically Modified Rodent Models in Drug Development to Explore Target Physiology and Potential Drug Effects

Zhong, Yu, Dambach, Donna M., Maher, Jonathan M.

Journal:

Veterinary Pathology

Year:

2018

Language:

english

File:

PDF, 101 KB

english, 2018

5

Pharmaceutical industry perspective on combination toxicity studies: Results from an IntRA-Industry survey conducted by IQ DRuSafe leadership group

Birkebak, Joanne, Buckley, Lorrene A., Dambach, Donna, Musvasva, Eunice, Price, Karen, Ralston, Sherry, Sacaan, Aida

Journal:

Regulatory Toxicology and Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.48 MB

english, 2018

6

HIV risk and pre-exposure prophylaxis interest among female bar workers in Dar es Salaam: cross-sectional survey

Harling, Guy, Muya, Aisa, Ortblad, Katrina F, Mashasi, Irene, Dambach, Peter, Ulenga, Nzovu, Barnhart, Dale, Mboggo, Eric, Oldenburg, Catherine E, Bärnighausen, Till, Spiegelman, Donna

Journal:

Year:

2019

File:

PDF, 385 KB

2019

7

A highly selective inhibitor of IκB kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice

Kim W. McIntyre, David J. Shuster, Kathleen M. Gillooly, Donna M. Dambach, Mark A. Pattoli, Pin Lu, Xia-Di Zhou, Yuping Qiu, F. Christopher Zusi, James R. Burke

Journal:

Arthritis & Rheumatism

Year:

2003

Language:

english

File:

PDF, 259 KB

english, 2003

8

Sry-Negative XX Sex Reversal in a Family of Norwegian Elkhounds

John R. Melniczek, Donna Dambach, Ulana Prociuk, Peter F. Jezyk, Paula S. Henthorn, Donald F. Patterson, Urs Giger

Journal:

Journal of Veterinary Internal Medicine

Year:

1999

Language:

english

File:

PDF, 299 KB

english, 1999

9

Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1: Potential role of inflammatory mediators

Carol R Gardner, Jeffrey D Laskin, Donna M Dambach, Hawjyh Chiu, Stephen K Durham, Peihong Zhou, Mary Bruno, Donald R Gerecke, Marion K Gordon, Debra L Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2003

Language:

english

File:

PDF, 677 KB

english, 2003

10

Identification of in vitro protein biomarkers of idiosyncratic liver toxicity

Ji Gao, Leah Ann Garulacan, Stephen M Storm, Stanley A Hefta, Gregory J Opiteck, Jun-Hsiang Lin, Frederic Moulin, Donna M Dambach

Journal:

Toxicology in Vitro

Year:

2004

Language:

english

File:

PDF, 319 KB

english, 2004

11

A MURINE MODEL OF CIGARETTE SMOKE-INDUCED PULMONARY INFLAMMATION USING INTRANASALLY ADMINISTERED SMOKE-CONDITIONED MEDIUM

Miller, Laura M., Foster, W. Michael, Dambach, Donna M., Doebler, Darryl, McKinnon, Murray, Killar, Loran, Longphre, Malinda

Journal:

Experimental Lung Research

Year:

2002

Language:

english

File:

PDF, 600 KB

english, 2002

12

Exploratory cardiovascular safety pharmacology in the lead-optimization of novel small molecule kinase inhibitors

Michael Flagella, Lewis Gazzard, Jason Halladay, Ryan Yokogawa, Lisa Wong, Joe Lubach, Beth Blackwood, Shiva Malek, Donna Dambach

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2011

Language:

english

File:

PDF, 50 KB

english, 2011

13

Jaw Lesions Resulting from Renal Hyperparathyroidism in a Young Dogâa Case Report

Sarkiala, Eva M., Dambach, Donna, Harvey, Colin E.

Journal:

Journal of Veterinary Dentistry

Year:

1994

File:

PDF, 3.90 MB

1994

14

Familial Dilated Cardiomyopathy of Young Portuguese Water Dogs

Donna M. Dambach, Anne Lannon, Meg M. Sleeper, James Buchanan

Journal:

Journal of Veterinary Internal Medicine

Year:

1999

Language:

english

File:

PDF, 300 KB

english, 1999

15

Coronavirus mouse hepatitis virus (MHV)-A59 causes a persistent, productive infection in primary glial cell cultures

Lavi, Ehud, Suzumura, Akio, Hirayama, Mikio, Highkin, Maureen K., Dambach, Donna M., Silberberg, Donald H., Weiss, Susan R.

Journal:

Microbial Pathogenesis

Year:

1987

Language:

english

File:

PDF, 1.28 MB

english, 1987

16

Current nonclinical testing paradigm enables safe entry to First-In-Human clinical trials: The IQ consortium nonclinical to clinical translational database

Monticello, Thomas M., Jones, Thomas W., Dambach, Donna M., Potter, David M., Bolt, Michael W., Liu, Maggie, Keller, Douglas A., Hart, Timothy K., Kadambi, Vivek J.

Journal:

Toxicology and Applied Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.24 MB

english, 2017

17

Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen-induced toxicity in mice

Hawjyh Chiu, Carol R Gardner, Donna M Dambach, Stephen K Durham, Jennie A Brittingham, Jeffrey D Laskin, Debra L Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2003

Language:

english

File:

PDF, 619 KB

english, 2003

18

Biomarker discovery in biological fluids

Ji Gao, Leah-Ann Garulacan, Stephen M. Storm, Gregory J. Opiteck, Yves Dubaquie, Stanley A. Hefta, Donna M. Dambach, Ashok R. Dongre

Journal:

Year:

2005

Language:

english

File:

PDF, 709 KB

english, 2005

19

Familial Protein-Losing Enteropathy and Protein-Losing Nephropathy in Soft Coated Wheaten Terriers: 222 Cases (1983–1997)

Meryl P. Littman, Donna M. Dambach, Shelly L. Vaden, Urs Giger

Journal:

Journal of Veterinary Internal Medicine

Year:

2000

Language:

english

File:

PDF, 902 KB

english, 2000

20

Dilated Cardiomyopathy in Juvenile Portuguese Water Dogs

Margaret M. Sleeper, Paula S. Henthorn, C. Vijayasarathy, Donna M. Dambach, Tim Bowers, Pierre Tijskens, Clara F. Armstrong, Edward B. Lankford

Journal:

Journal of Veterinary Internal Medicine

Year:

2002

Language:

english

File:

PDF, 1.00 MB

english, 2002

21

Integrated risk assessment of suicidal ideation and behavior in drug development

Muller, Patrick Y., Dambach, Donna, Gemzik, Brian, Hartmann, Andreas, Ratcliffe, Sian, Trendelenburg, Christian, Urban, Laszlo

Journal:

Drug Discovery Today

Year:

2015

Language:

english

File:

PDF, 317 KB

english, 2015

22

Cloning, expression and characterization of monkey (Macaca fascicularis) CD137

Shen-Jue Chen, William R. Foster, Maria N. Jure-Kunkel, Emel Girit, Ralph Abraham, Laura J. Hefta, Shan Gao, Christopher R. Yonan, Jun-Hsiang Lin, Donna M. Dambach

Journal:

Veterinary Immunology and Immunopathology

Year:

2008

Language:

english

File:

PDF, 519 KB

english, 2008

23

New Technologies and Screening Strategies for Hepatotoxicity: Use of In Vitro Models

Dambach, Donna, Andrews, Barbara, Moulin, Frederic

Journal:

Toxicologic Pathology

Year:

2005

Language:

english

File:

PDF, 1.12 MB

english, 2005

24

Safety Lead Optimization and Candidate Identification: Integrating New Technologies into Decision-Making

Dambach, Donna M, Misner, Dinah, Brock, Mathew, Fullerton, Aaron, Proctor, William, Maher, Jonathan, Lee, Dong, Ford, Kevin A., Diaz, Dolores

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

25

Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse

Donna M. Dambach, Linda M. Watson, Kevin R. Gray, Stephen K. Durham, Debra L. Laskin

Journal:

Year:

2002

Language:

english

File:

PDF, 437 KB

english, 2002

26

An Algorithm for Evaluating Potential Tissue Drug Distribution in Toxicology Studies from Readily Available Pharmacokinetic Parameters

Poulin, Patrick, Dambach, Donna M., Hartley, Dylan H., Ford, Kevin, Theil, Frank-Peter, Harstad, Eric, Halladay, Jason, Choo, Edna, Boggs, Jason, Liederer, Bianca M., Dean, Brian, Diaz, Dolores

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 954 KB

english, 2013

27

Distinct roles of NF-κB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity

Donna M. Dambach, Stephen K. Durham, Jeffrey D. Laskin, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 450 KB

english, 2006

28

Discovery of Highly Potent and Selective Bruton’s Tyrosine Kinase Inhibitors: Pyridazinone Analogs with Improved Metabolic Stability

Young, Wendy B., Barbosa, James, Blomgren, Peter, Bremer, Meire C., Crawford, James J., Dambach, Donna, Eigenbrot, Charles, Gallion, Steve, Johnson, Adam R., Kropf, Jeffrey E., Lee, Seung H., Liu, Lic

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 721 KB

english, 2015

29

Socio-demographic characteristics and risk factors for HIV transmission in female bar workers in sub-Saharan Africa: a systematic literature review

Dambach, Peter, Mahenge, Bathsheba, Mashasi, Irene, Muya, Aisa, Barnhart, Dale A., BÃ¤rnighausen, Till W., Spiegelman, Donna, Harling, Guy

Journal:

BMC Public Health

Year:

2020

File:

PDF, 1.04 MB

2020

30

Potent and selective Bruton’s tyrosine kinase inhibitors: Discovery of GDC-0834

Young, Wendy B., Barbosa, James, Blomgren, Peter, Bremer, Meire C., Crawford, James J., Dambach, Donna, Gallion, Steve, Hymowitz, Sarah G., Kropf, Jeffrey E., Lee, Seung H., Liu, Lichuan, Lubach, Jose

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 837 KB

english, 2015

31

A Retrospective Analysis of Toxicogenomics in the Safety Assessment of Drug Candidates

Foster, William R., Chen, Shen-Jue, He, Aiqing, Truong, Amy, Bhaskaran, Vasanthi, Nelson, David M., Dambach, Donna M., Lehman-McKeeman, Lois D., Car, Bruce D.

Journal:

Toxicologic Pathology

Year:

2007

Language:

english

File:

PDF, 6.54 MB

english, 2007

32

Role of p55 tumor necrosis factor receptor 1 in acetaminophen-induced antioxidant defense

Chiu, Hawjyh, Gardner, Carol R., Dambach, Donna M., Brittingham, Jennie A., Durham, Stephen K., Laskin, Jeffrey D., Laskin, Debra L.

Journal:

American Journal of Physiology - Gastrointestinal and Liver Physiology

Year:

2003

Language:

english

File:

PDF, 406 KB

english, 2003

33

Reduced Hepatotoxicity of Acetaminophen in Mice Lacking Inducible Nitric Oxide Synthase: Potential Role of Tumor Necrosis Factor-α and Interleukin-10

Carol R. Gardner, Jeffrey D. Laskin, Donna M. Dambach, Michael Sacco, Stephen K. Durham, Mary K. Bruno, Steven D. Cohen, Marion K. Gordon, Donald R. Gerecke, Peihong Zhou, Debra L. Laskin

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 629 KB

english, 2002

34

Potential Adverse Effects Associated with Inhibition of p38α/β MAP Kinases

Journal:

Current Topics in Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 81 KB

english, 2005

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